CAS 71751-41-2 Avermectin Abamectin Powder Veterinary Insecticide Powder Avermectin
Product name: Avermectin
CAS:71751-41-2
Appearance:White to yellowish crystalline
powder
Product Introduction
[[MetaDescription]]
Veterinary-Grade Broad-Spectrum Antiparasitic
Avermectin (CAS: 71751-41-2) is a widely used veterinary antiparasitic agent derived from *Streptomyces avermitilis*. It is highly effective against a broad range of internal and external parasites in livestock and poultry.
Due to its potent anthelmintic and acaricidal activity, Avermectin is frequently formulated into injectables, oral solutions, and topical preparations for use in cattle, swine, sheep, and poultry.
Broad Antiparasitic Action
Effective against nematodes, mites, and certain lice species in livestock
Multiple Dosage Forms
Available in injectable, oral, and pour-on forms to meet various clinical needs
Veterinary Use Only
Approved for use in animals only; not suitable for human pharmaceutical applications
Specification
1. Name and Identification
The active pharmaceutical ingredient is Avermectin (Veterinary Grade), CAS No. 71751-41-2. It is used to treat parasitic infestations in a variety of animal species.
2. Chemical Characteristics
Avermectin is a macrocyclic lactone compound with strong affinity for parasite chloride channels, leading to paralysis and death of the target organisms.
3. Physical Properties
It appears as a white to light yellow crystalline powder, practically insoluble in water, and stable under dry, cool conditions.
4. Specifications and Standards
| Test Parameter | Specification |
| Appearance | White to yellowish crystalline powder |
| Identification |
Consistent with reference standard |
| Loss on Drying | ≤ 2.0% |
|
Melting Point |
155–157°C |
|
Residue on Ignition |
≤ 0.1% |
| Assay (total avermectins) |
≥ 95.0% |
|
Heavy Metals |
≤ 10 ppm |
5. Veterinary Applications
Veterinary Avermectin is used in:
- Treatment of gastrointestinal and lung nematodes in cattle and sheep
- Control of external parasites such as mites and lice in pigs and poultry
- Component of pour-on and injectable formulations
- Preventative parasite control programs in large-scale animal husbandry
- Supports veterinary public health by reducing parasite transmission
Properties
Pharmacological Properties in Animal Systems
Avermectin is a macrocyclic lactone compound with potent anthelmintic and insecticidal properties used widely in veterinary practice:
- Mechanism of Action: Enhances the release of gamma-aminobutyric acid (GABA) at nerve endings, leading to paralysis and death of parasites.
- Spectrum of Activity: Effective against a wide range of ectoparasites and endoparasites, including mites, lice, and gastrointestinal roundworms.
- Pharmacokinetics in Animals: Administered via injection or topical formulations. Rapidly absorbed and exhibits prolonged action due to lipophilicity.
- Stability in Formulations: Stable in solid and liquid dosage forms under recommended storage conditions.
Chemical Properties
- pH in Solution: Typically formulated at neutral to slightly acidic pH for injectable or topical applications.
- Thermal Stability: Stable under dry and cool storage; avoid exposure to high temperatures and humidity.
- Light Sensitivity: Light-sensitive; store in opaque containers to preserve activity.
- Hygroscopicity: Moderately hygroscopic; handle in low-humidity environments to prevent degradation.
- Solubility Characteristics: Poorly soluble in water; soluble in organic solvents such as ethanol and propylene glycol.
Applications in Different Animal Species
Veterinary-grade Avermectin is used across species for effective parasite control:
- Cattle and Ruminants: Used to control gastrointestinal nematodes, lungworms, and ectoparasites.
- Swine: Treats mange mites, lice, and roundworm infestations effectively.
- Poultry: Applied under veterinary guidance for control of mites and other external parasites.
- Companion Animals: Used in dogs and cats in topical or oral formulations to treat and prevent parasite infestations.
Quality Control
Quality Control Measures for Veterinary API
Avermectin is subjected to strict quality control protocols to ensure its safety and efficacy in veterinary use:
Analytical Testing Methods:
- HPLC Analysis: Used to assess active ingredient content, related substances, and degradation profile
- UV-Vis Spectroscopy: Supports confirmation of chemical structure and identity
- Microbial Limit Testing: Ensures compliance with pharmacopeial microbial specifications
- Loss on Drying: Measures moisture levels using validated drying protocols
- Residual Solvents Testing: Conducted per ICH Q3C guidelines to ensure safe levels
Veterinary-Specific Quality Assurance:
Manufactured in GMP-compliant facilities with batch-level COA, MSDS, and traceability documentation for each order.
Stability and Compliance:
Stability is validated through real-time and accelerated studies to ensure consistent quality throughout shelf life.
Regulatory and Safety:
- Meets USP, EP, and VICH veterinary guideline requirements
- Produced at certified facilities for veterinary active ingredients
- Every batch undergoes full QC/QA release prior to dispatch
Packaging & Transportation
We offer protective and contamination-resistant packaging solutions for Avermectin (Veterinary API), combined with reliable global transport options tailored to your needs.
Packaging Options
Veterinary-Grade Packaging
1kg foil bag: Ideal for samples or pilot testing
25kg fiber drum: Double-layer PE liner for bulk supply
Custom options: Available upon request
Material compliance: Pharmaceutical-grade, moisture- and light-resistant
Transportation Options
Global Logistics Solutions
Express: DHL / FedEx / TNT for small urgent orders
Air freight: Fast option for medium-volume cargo
Sea freight: Economical for large-scale shipments
Lead time: Ships within 2–3 business days after payment
Company Certifications
Veterinary Compliance & Accreditation
- Veterinary GMP: Manufactured following veterinary GMP for consistent quality control.
- ISO 9001:2015: Quality system certification ensures batch consistency and risk reduction.
- ISO 14001:2015: Environmentally responsible production standards observed throughout manufacturing.
- Document Readiness: Includes COA, MSDS, batch traceability, and shipping documents.
Veterinary GMP
ISO 9001:2015
ISO 14001:2015
FAQ
Frequently Asked Questions About Fipronil
Q1: How to order the product?
A: You can chat with our online service directly.
You may also contact us via:
• Wechat: +86-18663729963, +86-13589106478
• Skype: sunnylee886
• Email: maggie@hope-biotech.com / sunny@hope-biotech.com
• Mobile: +86-18663729963, +86-13589106478
Q2: What kind of payment do you prefer?
A: We accept T/T, L/C, Western Union, and Paypal.
Q3: Can I get a sample before placing a bulk order?
A: Yes, we provide free samples for quality evaluation. Customers only need to cover the shipping cost.
Q4: What documents will you provide with the shipment?
A: Each shipment includes COA, MSDS, Packing List, Invoice, and relevant export regulatory documents. GMP/WC certificate can be provided if needed.
Q5: What is the product's shelf life?
A: Typically 24 months under recommended storage conditions (sealed, cool, dry environment).
Q6: Do you support DDP or door-to-door delivery?
A: Yes, for selected countries and based on order volume, we offer DDP and customs clearance support.
Q7: What is your lead time after order confirmation?
A: Usually 5–10 working days for stock items. For customized or non-stock products, lead time will be confirmed after consultation.
Q8: What are your loading ports?
A: We commonly ship from Shanghai, Qingdao, or Tianjin, depending on product location and customer preference.
Q9: What is the minimum order quantity (MOQ)?
A: Our MOQ is flexible depending on the product. For most items, we support orders as low as 100g for trial use.
Q10: Is your product safe and compliant for veterinary or pharmaceutical use?
A: Yes. All our products meet GMP or ISO standards, tested batch-by-batch, and are suitable for further formulation in veterinary or pharmaceutical applications.
[[ContDescription]]
Hot Tags: avermectin, China, suppliers, manufacturers, factory, Veterinary Preparation, Fipronil, Florfenical, Tylosin Phosphate, Florfenical Soluble Powder 50 , Ampicillin Sodium Soluble Powder 50
[[ProKeywords]]